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Biotinylated Mouse Fc gamma RIII/CD16 Protein 2171

$525.00$1,750.00

Summary

  • Expression: HEK293
  • Binding assay: Yes (SPR)
  • Amino Acid Range: Leu32-Thr215
SKU: 2171parent Categories: , Tag:
Weight1 lbs
Dimensions9 × 5 × 2 in
express system

HEK293

product tag

C-His-Avi

purity

> 95% as determined by Tris-Bis PAGE

background

Immunoglobulin G (IgG) Fc receptors play a critical role in linking IgG antibody-mediated immune responses with cellular effector functions. A high resolution map of the binding site on human IgG1 for human Fc gamma RI, Fc gamma RIIA, Fc gamma RIIB, Fc gamma RIIIA, and FcRn receptors has been determined.A common set of IgG1 residues is involved in binding to all Fc gamma R; Fc gamma RII and Fc gamma RIII also utilize residues outside this common set.

molecular weight

The protein has a predicted MW of 23.97 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.

available size

100 µg, 500 µg

endotoxin

Less than 1EU per μg by the LAL method.

Biotinylated Mouse Fc gamma RIII/CD16 Protein 2171

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
Immunoglobulin G (IgG) Fc receptors play a critical role in linking IgG antibody-mediated immune responses with cellular effector functions. A high resolution map of the binding site on human IgG1 for human Fc gamma RI, Fc gamma RIIA, Fc gamma RIIB, Fc gamma RIIIA, and FcRn receptors has been determined.A common set of IgG1 residues is involved in binding to all Fc gamma R; Fc gamma RII and Fc gamma RIII also utilize residues outside this common set.
Protein names
Fc gamma receptor III
Gene names
Fcgr3,Fcgr3
Mass
10090Da
Target Relevance information above includes information from UniProt accession: Q5D5I8
The UniProt Consortium

SPR with Biotinylated Mouse Fc gamma RIII/CD16 Protein
OKT3 captured on CM5 Chip via Protein A can bind Biotinylated Mouse Fc gamma RIII, His Tag with an affinity constant of 0.164 µM as determined in SPR assay (Biacore T200).
HPLC of Biotinylated Mouse Fc gamma RIII/CD16 Protein
The purity of Biotinylated Mouse Fc gamma RIII is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Biotinylated Mouse Fc gamma RIII/CD16 Protein
Biotinylated Mouse Fc gamma RIII on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

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We haven't added any publications to our database yet.
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.

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