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Biotinylated Human ROR2/NTRKR2 Protein 4870

$525.00$1,750.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Val34-Gly403
SKU: 4870parent Categories: , Tags: , , ,
Weight1 lbs
Dimensions9 × 5 × 2 in
product tag

C-His-Avi, also biotinylated

Biotinylated Human ROR2/NTRKR2 Protein 4870

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the development of the central nervous system. Mature human ROR2 contains a 369 amino acid (aa) extracellular domain (ECD) and a 518 aa cytoplasmic tail containing an tyrosine kinase domain.
Protein names
Receptor tyrosine kinase-like orphan receptor 2
Gene names
ROR2,ROR2
Protein family
Protein kinase superfamily, Tyr protein kinase family, ROR subfamily
Mass
9606Da
Catalytic activity
BINDING 479..487; /ligand="ATP"; /ligand_id="ChEBI:CHEBI:30616"; /evidence="ECO:0000256|PIRSR:PIRSR000624-2"; BINDING 507; /ligand="ATP"; /ligand_id="ChEBI:CHEBI:30616"; /evidence="ECO:0000256|PIRSR:PIRSR000624-2"
Subellular location
SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Target Relevance information above includes information from UniProt accession : A1L4F5
The UniProt Consortium

Data

ELISA with Biotinylated Human ROR2/NTRKR2 Protein
Immobilized Anti-ROR2 Antibody, hFc Tag at 0.5µg/ml (100µl/Well) on the plate. Dose response curve for Biotinylated Human ROR2, hFc Tag with the EC50 of 6.5ng/ml determined by ELISA.
HPLC of Biotinylated Human ROR2/NTRKR2 Protein
The purity of Biotinylated Human ROR2 is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Biotinylated Human ROR2/NTRKR2 Protein
Biotinylated Human ROR2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




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Protocols

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