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Biotinylated Human MICA Protein 4869

$525.00$1,750.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Glu24-Gln308
SKU: 4869parent Categories: , Tags: , , ,
Weight1 lbs
Dimensions9 × 5 × 2 in
product tag

C-His-Avi, also biotinylated

Biotinylated Human MICA Protein 4869

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
TMICA (MHC class I chain-related gene A) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. A closely related protein, MICB, shares 85% amino acid identity with MICA. These proteins are distantly related to the MHC class I proteins. They possess three extracellular Ig‑like domains, but they have no capacity to bind peptide or interact with beta 2-microglobulin.
Protein names
MHC class I chain-related protein A (MHC class I polypeptide-related sequence A) (MICA) (Stress inducible class I homolog)
Gene names
MICA,MICA hCG_2001511
Mass
9606Da
Catalytic activity
BINDING 248; /ligand="Zn(2+)"; /ligand_id="ChEBI:CHEBI:29105"; /evidence="ECO:0007829|PDB:6DDR"; BINDING 249; /ligand="Zn(2+)"; /ligand_id="ChEBI:CHEBI:29105"; /evidence="ECO:0007829|PDB:6DDR"
Target Relevance information above includes information from UniProt accession : Q96QC4
The UniProt Consortium

Data

ELISA with Biotinylated Human MICA Protein
Immobilized Anti-MICA Antibody, hFc Tag at 5µg/ml (100µl/Well) on the plate. Dose response curve for Biotinylated Human MICA, His Tag with the EC50 of 1.7µg/ml determined by ELISA (QC Test).
ELISA with Biotinylated Human MICA Protein
Immobilized Human NKG2D, hFc Tag at 2µg/ml (100µl/Well) on the plate. Dose response curve for Biotinylated Human MICA, His Tag with the EC50 of 0.32µg/ml determined by ELISA.
HPLC of Biotinylated Human MICA Protein
The purity of Biotinylated Human MICA is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Biotinylated Human MICA Protein
Biotinylated Human MICA on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




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Protocols

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