Weight | 1 lbs |
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Dimensions | 9 × 5 × 2 in |
accession | Q9NZD1 |
express system | HEK293 |
product tag | |
purity | > 95% as determined by HPLC |
background | Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA. |
molecular weight | The target protein has a predicted MW of 39.6 kDa. |
available size | 100 µg, 500 µg |
endotoxin | Less than 1EU per μl by the LAL method. |
Biotinylated Human GPRC5D Protein-VLP 4303
$1,969.00
Summary
- Expression: HEK293
- Functional: Yes (ELISA)
- Amino Acid Range: Met1-Val345
Biotinylated Human GPRC5D Protein-VLP 4303
protein |
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Size and concentration 100, 500µg and liquid |
Form Liquid |
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Storage buffer Shipped with dry ice. |
Purity > 95% as determined by Tris-Bis PAGE |
target relevance |
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Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA. |
Protein names G-protein coupled receptor family C group 5 member D |
Gene names GPRC5D,GPRC5D |
Protein family G-protein coupled receptor 3 family |
Mass 9606Da |
Subellular location Cell membrane ; Multi-pass membrane protein . |
Tissues Widely expressed in the peripheral system. Expression pattern is high in pancreas, medium in kidney, small intestine, spleen and testis, low in lung, colon, leukocyte, prostate and thymus and not detectable in brain, heart, liver, placenta, skeletal muscle and ovary. |
Target Relevance information above includes information from UniProt accession: Q9NZD1 |
The UniProt Consortium |
Data
Publications
Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.pmid | title | authors | citation |
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Protocols
relevant to this product |
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Documents
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