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Biotinylated Human CD5 Protein 4678

$525.00$1,750.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Arg25-Asn371
SKU: 4678parent Categories: , Tags: , , ,
Weight1 lbs
Dimensions9 × 5 × 2 in
product tag

C-hFc-Avi, also biotinylated

Biotinylated Human CD5 Protein 4678

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; expressed in B-cell chronic lymphocytic leukemia and T-cell lymphoma.
Protein names
T-cell surface glycoprotein CD5 (Lymphocyte antigen T1/Leu-1) (CD antigen CD5)
Gene names
CD5,CD5 LEU1
Mass
9606Da
Function
FUNCTION: May act as a receptor in regulating T-cell proliferation.
Subellular location
SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein.
Structure
SUBUNIT: Interacts with CD72/LYB-2. Interacts with PTPN6/SHP-1 (By similarity). {ECO:0000250}.
Post-translational modification
PTM: Phosphorylated on tyrosine residues by LYN; this creates binding sites for PTPN6/SHP-1. {ECO:0000250}.
Target Relevance information above includes information from UniProt accession : P06127
The UniProt Consortium

Data

ELISA with Biotinylated Human CD5 Protein
Immobilized Anti-CD5 Antibody, hFc Tag at 1µg/ml (100µl/Well) on the plate. Dose response curve for Biotinylated Human CD5, hFc Tag with the EC50 of 8.6ng/ml determined by ELISA.
HPLC of Biotinylated Human CD5 Protein
The purity of Biotinylated Human CD5 is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Biotinylated Human CD5 Protein
Biotinylated Human CD5 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




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Protocols

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