no metadatahttps://benchmarkantibodies.com/product/biotinylated-human-bcma-tnfrsf17-trimer-protein-4580/
Skip to content

Biotinylated Human BCMA/TNFRSF17 Trimer Protein 4580

$525.00$1,750.00

Summary

  • Expression: HEK293
  • Functional: Yes (ELISA)
  • Amino Acid Range: Met1-Ala54
Weight1 lbs
Dimensions9 × 5 × 2 in
product tag

C-His-Avi, also biotinylated

Biotinylated Human BCMA/TNFRSF17 Trimer Protein 4580

protein
Size and concentration
100, 500µg and lyophilized
Form
Lyophilized
Storage Instructions
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer
Shipped at ambient temperature.
Purity
> 95% as determined by Tris-Bis PAGE
target relevance
B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF).
Protein names
Tumor necrosis factor receptor superfamily member 17 (B-cell maturation protein) (CD antigen CD269)
Gene names
TNFRSF17,TNFRSF17 BCM BCMA
Mass
20165Da
Function
FUNCTION: Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. {ECO:0000269|PubMed:10801128, ECO:0000269|PubMed:10903733, ECO:0000269|PubMed:10973284}.
Subellular location
SUBCELLULAR LOCATION: Cell membrane; Single-pass type III membrane protein. Endomembrane system; Single-pass type III membrane protein. Note=Perinuclear Golgi-like structures.
Tissues
TISSUE SPECIFICITY: Expressed in mature B-cells, but not in T-cells or monocytes.
Structure
SUBUNIT: Associates with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6. {ECO:0000269|PubMed:12721620, ECO:0000269|PubMed:15542592}.
Domain
TOPO_DOM 1
Target Relevance information above includes information from UniProt accession : Q02223
The UniProt Consortium

Data

ELISA with Biotinylated Human BCMA/TNFRSF17 Trimer Protein
Immobilized Human BAFF, hFc Tag at 1µg/ml (100µl/Well) on the plate. Dose response curve for Biotinylated Human BCMA Trimer, His Tag with the EC50 of 11.1ng/ml determined by ELISA (QC Test).
ELISA with Biotinylated Human BCMA/TNFRSF17 Trimer Protein
Immobilized Anti-BCMA Antibody at 1µg/ml (100µl/Well) on the plate. Dose response curve for Biotunylated Human BCMA Trimer, His Tag with the EC50 of 1.9ng/ml determined by ELISA.
HPLC of Biotinylated Human BCMA/TNFRSF17 Trimer Protein
The purity of Biotunylated Human BCMA Trimer is greater than 95% as determined by SEC-HPLC.
SDS-PAGE gel of Biotinylated Human BCMA/TNFRSF17 Trimer Protein
Biotunylated Human BCMA Trimer on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.




pmidtitleauthorscitation

Protocols

relevant to this product

Documents

#
No results found

Reviews

There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.