ELISA with Biotinylated Human APRIL/TNFSF13 Trimer Protein (Primary Ami 2557

HPLC of Biotinylated Human APRIL/TNFSF13 Trimer Protein (Primary Amine 2557

SDS-PAGE gel of Biotinylated Human APRIL/TNFSF13 Trimer Protein (Primar 2557

Biotinylated Human APRIL/TNFSF13 Trimer Protein (Primary Amine Labeling) 2557

$525.00 – $1,750.00

Summary

Expression: HEK293
Functional: Yes (ELISA)
Amino Acid Range: Lys112-Leu250

SKU: 2557parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
express system	HEK293
product tag	N-His-Flag
purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
background	The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close relative BAFF bind and signal through the TNF superfamily receptors TACI and BCMA, while BAFF additionally functions through BAFF R.
molecular weight	The protein has a predicted MW of 49.9 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Biotinylated Human APRIL/TNFSF13 Trimer Protein (Primary Amine Labeling) 2557

protein

Size and concentration 100, 500µg and lyophilized
Form Lyophilized
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped at ambient temperature.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close relative BAFF bind and signal through the TNF superfamily receptors TACI and BCMA, while BAFF additionally functions through BAFF R.
Protein names Tumor necrosis factor ligand superfamily member 13 (A proliferation-inducing ligand) (APRIL) (TNF- and APOL-related leukocyte expressed ligand 2) (TALL-2) (TNF-related death ligand 1) (TRDL-1) (CD antigen CD256)
Gene names TNFSF13,TNFSF13 APRIL TALL2 ZTNF2 UNQ383/PRO715
Protein family Tumor necrosis factor family
Mass 27433Da
Function Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes.
Subellular location Secreted .
Tissues Expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages.
Structure Homotrimer.
Post-translational modification The precursor is cleaved by furin.
Target Relevance information above includes information from UniProt accession: O75888
The UniProt Consortium

ELISA with Biotinylated Human APRIL/TNFSF13 Trimer Protein (Primary Ami

Immobilized Human BCMA, hFc Tag at 0.5µg/ml (100µl/Well) on the plate. Dose response curve for Biotinylated Human APRIL (Trimer) , His Tag with the EC50 of 5.2ng/ml determined by ELISA.

HPLC of Biotinylated Human APRIL/TNFSF13 Trimer Protein (Primary Amine

The purity of Biotinylated Human APRIL Trimer is greater than 95% as determined by SEC-HPLC.

SDS-PAGE gel of Biotinylated Human APRIL/TNFSF13 Trimer Protein (Primar

Biotinylated Human APRIL Trimer on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

pmid	title	authors	citation
We haven't added any publications to our database yet.

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.