SDS-PAGE gel of Biotinylated Cynomolgus PADI4 Protein (Primary Amine La 3087

Biotinylated Cynomolgus PADI4 Protein (Primary Amine Labeling) 3087

$675.00 – $2,250.00

Summary

Expression: E.coli
Pure: Yes (SDS-PAGE)
Amino Acid Range: Met1-Pro663

SKU: 3087parent Categories: proteins, Recombinant proteins Tag: active proteins

Weight	1 lbs
Dimensions	9 × 5 × 2 in
express system	E.coli
product tag	N-His
purity	> 95% as determined by Tris-Bis PAGE
background	Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has post-translational modification activity (citrullination). Padi4 is mainly expressed in myeloid cells and granulocytes.
molecular weight	The protein has a predicted MW of 76.6 kDa same as Tris-Bis PAGE result.
available size	100 µg, 500 µg
endotoxin	Less than 1EU per μg by the LAL method.

Biotinylated Cynomolgus PADI4 Protein (Primary Amine Labeling) 3087

protein

Size and concentration 100, 500µg and liquid
Form Liquid
Storage Instructions Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Storage buffer Shipped with dry ice.
Purity > 95% as determined by Tris-Bis PAGE

target relevance
Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has post-translational modification activity (citrullination). Padi4 is mainly expressed in myeloid cells and granulocytes.
Protein names Protein-arginine deiminase (EC 3.5.3.15)
Gene names PADI4,PADI4
Protein family Protein arginine deiminase family
Mass 9541Da
Function Catalyzes the deimination of arginine residues of proteins.
Subellular location Cytoplasm .
Target Relevance information above includes information from UniProt accession: A0A2K5USI5
The UniProt Consortium

Data

SDS-PAGE gel of Biotinylated Cynomolgus PADI4 Protein (Primary Amine La

Biotinylated Cynomolgus PADI4 (Primary Amine Labeling) on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Publications

Published literature highly relevant to the biological target of this product and referencing this antibody or clone are retrieved from PubMed database provided by The United States National Library of Medicine at the National Institutes of Health.